STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SEMA6Csemaphorin-6C; Belongs to the semaphorin family. (804 aa)    
Predicted Functional Partners:
PLXNA1
LOW QUALITY PROTEIN: plexin-A1.
    
 0.842
PLXND1
LOW QUALITY PROTEIN: plexin-D1.
    
 0.782
NRP1
Neuropilin; Belongs to the neuropilin family.
    
 0.713
PLXNA2
LOW QUALITY PROTEIN: plexin-A2.
    
 0.709
MET
Hepatocyte growth factor receptor.
    
 0.659
MST1R
Macrophage-stimulating protein receptor.
    
 0.659
PLXNC1
plexin-C1.
    
 0.623
PLXNA4
plexin-A4 isoform X1.
    
 0.541
EFNB1
ephrin-B1; Belongs to the ephrin family.
      
 0.513
PLXNB2
LOW QUALITY PROTEIN: plexin-B2.
    
0.481
Your Current Organism:
Ursus maritimus
NCBI taxonomy Id: 29073
Other names: Thalarctos maritimus, U. maritimus, polar bear, white bear
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.