STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PIGZMannosyltransferase. (563 aa)    
Predicted Functional Partners:
PIGO
Phosphatidylinositol glycan anchor biosynthesis class O.
    
 
 0.828
PIGY
Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y.
      
 0.818
PIGV
GPI mannosyltransferase 2; Mannosyltransferase involved in glycosylphosphatidylinositol- anchor biosynthesis.
    
 
 0.803
PIGG
GPI ethanolamine phosphate transferase 2 isoform X3.
 
  
 
 0.791
TMEM165
Transmembrane protein 165.
      
 0.790
SLC35A2
UDP-galactose translocator.
      
 0.783
SYVN1
E3 ubiquitin-protein ligase synoviolin.
      
 0.781
DERL2
Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.
      
 0.778
AMFR
E3 ubiquitin-protein ligase AMFR.
      
 0.775
DERL1
Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.
      
 0.775
Your Current Organism:
Ursus maritimus
NCBI taxonomy Id: 29073
Other names: Thalarctos maritimus, U. maritimus, polar bear, white bear
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