STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DIO3Iodothyronine deiodinase; Responsible for the deiodination of T4 (3,5,3',5'- tetraiodothyronine). (131 aa)    
Predicted Functional Partners:
DIO2
Iodothyronine deiodinase; Responsible for the deiodination of T4 (3,5,3',5'- tetraiodothyronine).
      
 0.646
EYA3
Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family.
      
 0.602
PEG3
Paternally-expressed gene 3 protein.
      
 0.567
HLF
HLF transcription factor, PAR bZIP family member.
      
 0.552
UHRF1BP1
UHRF1-binding protein 1.
    
 
 0.534
MACF1
Microtubule-actin cross-linking factor 1.
      
 0.515
MACF1-2
Microtubule-actin crosslinking factor 1.
      
 0.515
PEG10
LOW QUALITY PROTEIN: retrotransposon-derived protein PEG10.
      
 0.449
LOC103660022
LOW QUALITY PROTEIN: necdin.
      
 0.449
THRA
Thyroid hormone receptor alpha.
      
 0.448
Your Current Organism:
Ursus maritimus
NCBI taxonomy Id: 29073
Other names: Thalarctos maritimus, U. maritimus, polar bear, white bear
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