STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MMP11Stromelysin-3. (454 aa)    
Predicted Functional Partners:
FURIN
LOW QUALITY PROTEIN: furin; Belongs to the peptidase S8 family.
    
 0.891
TIMP2
Metalloproteinase inhibitor 2 isoform X1.
   
 0.665
TIMP3
TIMP metallopeptidase inhibitor 3.
   
 0.654
SPP1
Secreted phosphoprotein 1.
     
 0.609
MMP7
Matrix metallopeptidase 7.
  
  
0.581
MMP20
Matrix metalloproteinase-20.
  
0.522
FBLN1
Fibulin-1; Incorporated into fibronectin-containing matrix fibers. May play a role in cell adhesion and migration along protein fibers within the extracellular matrix (ECM). Could be important for certain developmental processes and contribute to the supramolecular organization of ECM architecture, in particular to those of basement membranes.
   
 0.520
EPDR1
Mammalian ependymin-related protein 1.
      
 0.491
MMP2
72 kDa type IV collagenase.
   
0.489
MMP19
Matrix metalloproteinase-19.
  
 
0.463
Your Current Organism:
Ursus maritimus
NCBI taxonomy Id: 29073
Other names: Thalarctos maritimus, U. maritimus, polar bear, white bear
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.