STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KLF11Krueppel-like factor 11. (501 aa)    
Predicted Functional Partners:
SIN3A
SIN3 transcription regulator family member A.
    
 
 0.654
TBC1D13
TBC1 domain family member 13 isoform X1.
      
 0.599
PEX6
LOW QUALITY PROTEIN: peroxisome biogenesis factor 6.
    
 
 0.596
WDR92
WD repeat-containing protein 92.
    
 0.575
PPP1CA
Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family.
    
 0.494
ATP6V1C2
V-type proton ATPase subunit C; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.
     
 0.483
PPP1CC
Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family.
    
 0.460
KLF9
Krueppel-like factor 9.
      
 0.441
SIN3B
Paired amphipathic helix protein Sin3b.
    
 
 0.438
RXRA
Retinoic acid receptor RXR-alpha.
    
 0.436
Your Current Organism:
Ursus maritimus
NCBI taxonomy Id: 29073
Other names: Thalarctos maritimus, U. maritimus, polar bear, white bear
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.