STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CASP14Caspase-14; Belongs to the peptidase C14A family. (242 aa)    
Predicted Functional Partners:
XIAP
E3 ubiquitin-protein ligase XIAP.
   
 0.802
BLMH
Bleomycin hydrolase; Belongs to the peptidase C1 family.
    
 
 0.765
SERPINB12
Serpin B12; Belongs to the serpin family.
   
 
 0.737
APAF1
Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.
    
 0.731
CENPN
Centromere protein N.
   
 0.725
CENPI
Centromere protein I.
   
 0.697
CENPQ
Centromere protein Q isoform X1.
   
 0.694
CENPP
Centromere protein P isoform X1.
   
 0.683
CENPM
Centromere protein M.
   
 0.672
CENPH
Centromere protein H.
   
 0.659
Your Current Organism:
Ursus maritimus
NCBI taxonomy Id: 29073
Other names: Thalarctos maritimus, U. maritimus, polar bear, white bear
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.