STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LGI2Leucine-rich repeat LGI family member 2. (488 aa)    
Predicted Functional Partners:
ADAM22
Disintegrin and metalloproteinase domain-containing protein 22.
     
 0.940
ADAM23
Disintegrin and metalloproteinase domain-containing protein 23.
     
 0.940
ADAM11
Disintegrin and metalloproteinase domain-containing protein 11.
     
 0.825
CCDC141
Coiled-coil domain-containing protein 141 isoform X2.
    
 0.745
CECR2
Cat eye syndrome critical region protein 2.
    
 0.697
NETO2
Neuropilin and tolloid-like protein 2.
      
 0.684
CLPB
Caseinolytic peptidase B protein homolog isoform X1.
    
 
 0.639
NXPH3
Neurexophilin; May be signaling molecules that resemble neuropeptides.
      
 0.636
CELF6
CUGBP Elav-like family member 6.
      
 0.635
SEPSECS
O-phosphoseryl-tRNA(Sec) selenium transferase; Converts O-phosphoseryl-tRNA(Sec) to selenocysteinyl- tRNA(Sec) required for selenoprotein biosynthesis.
 
  
 
 0.587
Your Current Organism:
Ursus maritimus
NCBI taxonomy Id: 29073
Other names: Thalarctos maritimus, U. maritimus, polar bear, white bear
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