STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ARHGEF1LOW QUALITY PROTEIN: rho guanine nucleotide exchange factor 1. (944 aa)    
Predicted Functional Partners:
GNA13
Guanine nucleotide-binding protein subunit alpha-13.
    
 0.990
RHOC
Rho-related GTP-binding protein RhoC.
   
 0.863
RHOA
Ras homolog family member A.
   
 0.863
GNA12
Guanine nucleotide-binding protein subunit alpha-12.
    
 0.804
FCAR
Immunoglobulin alpha Fc receptor isoform X1.
      
 0.648
MKNK2
MAP kinase-interacting serine/threonine-protein kinase 2; Belongs to the protein kinase superfamily.
      
 0.646
ENSUMAP00000007470
annotation not available
   
 0.637
AP3M1
AP-3 complex subunit mu-1; Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes; Belongs to the adaptor complexes medium subunit family.
      
 0.635
ARHGEF6
LOW QUALITY PROTEIN: rho guanine nucleotide exchange factor 6.
    
 0.608
HEATR5A
HEAT repeat-containing protein 5A isoform X1.
   
  
 0.603
Your Current Organism:
Ursus maritimus
NCBI taxonomy Id: 29073
Other names: Thalarctos maritimus, U. maritimus, polar bear, white bear
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.