STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CEP55Centrosomal protein of 55 kDa. (463 aa)    
Predicted Functional Partners:
DLGAP5
Disks large-associated protein 5 isoform X1.
   
  
 0.964
KIF11
Kinesin-like protein KIF11; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
   
  
 0.948
TTK
Dual specificity protein kinase TTK isoform X2.
   
  
 0.946
TSG101
Tumor susceptibility gene 101 protein.
    
 
 0.932
ASPM
Abnormal spindle microtubule assembly.
   
  
 0.920
RACGAP1
Rac GTPase-activating protein 1.
   
 
 0.919
KIF20A
Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
   
 
 0.919
RRM2
Ribonucleoside-diphosphate reductase subunit M2.
   
  
 0.918
SPAG5
LOW QUALITY PROTEIN: sperm-associated antigen 5.
   
 
 0.909
TOP2A
DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks.
   
  
 0.909
Your Current Organism:
Ursus maritimus
NCBI taxonomy Id: 29073
Other names: Thalarctos maritimus, U. maritimus, polar bear, white bear
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.