STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CNTRLLOW QUALITY PROTEIN: centriolin. (2323 aa)    
Predicted Functional Partners:
PLK1
Serine/threonine-protein kinase PLK.
   
 0.840
NIN
LOW QUALITY PROTEIN: ninein.
   
 0.792
CEP170
Centrosomal protein of 170 kDa.
    
 0.773
CEP128
Centrosomal protein of 128 kDa.
    
 0.762
CCDC68
Coiled-coil domain-containing protein 68.
     
 0.757
ODF2
Outer dense fiber protein 2 isoform X2.
   
 0.659
PUF60
LOW QUALITY PROTEIN: poly(U)-binding-splicing factor PUF60.
    
 
 0.643
TCHHL1
Trichohyalin-like protein 1.
    
 0.642
RPF2
Ribosome production factor 2 homolog.
      
 0.636
DPM1
Dolichol-phosphate mannosyltransferase subunit 1; Transfers mannose from GDP-mannose to dolichol monophosphate to form dolichol phosphate mannose (Dol-P-Man) which is the mannosyl donor in pathways leading to N-glycosylation, glycosyl phosphatidylinositol membrane anchoring, and O-mannosylation of proteins.
      
 0.634
Your Current Organism:
Ursus maritimus
NCBI taxonomy Id: 29073
Other names: Thalarctos maritimus, U. maritimus, polar bear, white bear
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.