STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NKX2-2NK2 homeobox 2. (306 aa)    
Predicted Functional Partners:
NEUROG3
Neurogenin-3.
   
 0.886
PAX6
Paired box protein Pax-6 isoform X2.
    
 
 0.652
UTS2
Urotensin-2.
      
 0.641
INS-IGF2
Insulin, isoform 2-like; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.
   
 
 0.615
OLIG3
Oligodendrocyte transcription factor 3.
   
 0.575
TG
LOW QUALITY PROTEIN: thyroglobulin.
      
 0.568
NEUROD4
Neurogenic differentiation factor.
   
 0.552
ENSUMAP00000007732
annotation not available
    
 
 0.552
CHGA
Chromogranin A.
      
 0.542
KCNJ11
Potassium voltage-gated channel subfamily J member 11.
      
 0.511
Your Current Organism:
Ursus maritimus
NCBI taxonomy Id: 29073
Other names: Thalarctos maritimus, U. maritimus, polar bear, white bear
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