STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LTA4HLeukotriene A(4) hydrolase; Belongs to the peptidase M1 family. (704 aa)    
Predicted Functional Partners:
ALOX5
Arachidonate 5-lipoxygenase.
    
 0.936
CYP4F3
leukotriene-B(4) omega-hydroxylase 2 isoform X1; Belongs to the cytochrome P450 family.
    
 0.910
TRIT1
tRNA dimethylallyltransferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37; Belongs to the IPP transferase family.
 
      0.820
ALOX5AP
Arachidonate 5-lipoxygenase-activating protein.
      
 0.636
GFM1
Elongation factor G, mitochondrial; Mitochondrial GTPase that catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome. Does not mediate the disassembly of ribosomes from messenger RNA at the termination of mito [...]
   
 
 0.575
FXR1
Fragile X mental retardation syndrome-related protein 1 isoform X3.
      
 0.497
MRPL13
39S ribosomal protein L13, mitochondrial; Belongs to the universal ribosomal protein uL13 family.
 
 
 
 0.470
S100A8
Protein S100; Belongs to the S-100 family.
    
 
 0.466
PIK3R5
LOW QUALITY PROTEIN: phosphoinositide 3-kinase regulatory subunit 5.
      
 0.457
CNOT7
CCR4-NOT transcription complex subunit 7.
   
  
 0.453
Your Current Organism:
Ursus maritimus
NCBI taxonomy Id: 29073
Other names: Thalarctos maritimus, U. maritimus, polar bear, white bear
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.