STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ERGIC3Endoplasmic reticulum-Golgi intermediate compartment protein 3 isoform X1. (388 aa)    
Predicted Functional Partners:
ERGIC2
Endoplasmic reticulum-Golgi intermediate compartment protein 2.
   
0.984
GTPBP3
tRNA modification GTPase GTPBP3, mitochondrial.
  
 0.937
VPS45
Vacuolar protein sorting-associated protein 45; Belongs to the STXBP/unc-18/SEC1 family.
 
      0.900
BLOC1S1
Biogenesis of lysosome-related organelles complex 1 subunit 1.
   
  
 0.737
CNPY4
Canopy FGF signaling regulator 4.
 
 
    0.723
MED31
Mediator of RNA polymerase II transcription subunit 31; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
 
      0.683
TRMU
LOW QUALITY PROTEIN: mitochondrial tRNA-specific 2-thiouridylase 1.
  
 0.656
GTSE1
G2 and S phase-expressed protein 1.
  
 0.656
CDC42SE2
CDC42 small effector protein 2.
   
 
 0.531
TMX3
Thioredoxin related transmembrane protein 3.
   
 
 0.520
Your Current Organism:
Ursus maritimus
NCBI taxonomy Id: 29073
Other names: Thalarctos maritimus, U. maritimus, polar bear, white bear
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.