VTCN1 protein (Ursus maritimus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

VTCN1

V-set domain-containing T-cell activation inhibitor 1. (275 aa)

Predicted Functional Partners:

CEACAM19

0.672

LOC103656170

0.620

SPTLC3

0.582

CTLA4

0.527

BBOX1

0.517

TMIGD2

0.513

PDCD1LG2

0.512

TNFSF9

0.508

TNFSF4

0.504

TNFRSF18

0.495

Your Current Organism:

Ursus maritimus

NCBI taxonomy Id: 29073
Other names: Thalarctos maritimus, U. maritimus, polar bear, white bear

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BBOX1	VTCN1	ENSUMAP00000027212	ENSUMAP00000005893	Gamma-butyrobetaine hydroxylase 1.	V-set domain-containing T-cell activation inhibitor 1.	0.517
CEACAM19	SPTLC3	ENSUMAP00000032146	ENSUMAP00000011359	Carcinoembryonic antigen-related cell adhesion molecule 19.	Serine palmitoyltransferase long chain base subunit 3.	0.573
CEACAM19	VTCN1	ENSUMAP00000032146	ENSUMAP00000005893	Carcinoembryonic antigen-related cell adhesion molecule 19.	V-set domain-containing T-cell activation inhibitor 1.	0.672
CTLA4	PDCD1LG2	ENSUMAP00000030761	ENSUMAP00000022872	Cytotoxic T-lymphocyte associated protein 4.	LOW QUALITY PROTEIN: programmed cell death 1 ligand 2.	0.558
CTLA4	TNFRSF18	ENSUMAP00000030761	ENSUMAP00000002791	Cytotoxic T-lymphocyte associated protein 4.	Tumor necrosis factor receptor superfamily member 18.	0.521
CTLA4	VTCN1	ENSUMAP00000030761	ENSUMAP00000005893	Cytotoxic T-lymphocyte associated protein 4.	V-set domain-containing T-cell activation inhibitor 1.	0.527
LOC103656170	VTCN1	ENSUMAP00000003817	ENSUMAP00000005893	Antigen WC1.1-like isoform X1.	V-set domain-containing T-cell activation inhibitor 1.	0.620
PDCD1LG2	CTLA4	ENSUMAP00000022872	ENSUMAP00000030761	LOW QUALITY PROTEIN: programmed cell death 1 ligand 2.	Cytotoxic T-lymphocyte associated protein 4.	0.558
PDCD1LG2	TNFSF9	ENSUMAP00000022872	ENSUMAP00000015300	LOW QUALITY PROTEIN: programmed cell death 1 ligand 2.	Tumor necrosis factor ligand superfamily member 9; Belongs to the tumor necrosis factor family.	0.437
PDCD1LG2	VTCN1	ENSUMAP00000022872	ENSUMAP00000005893	LOW QUALITY PROTEIN: programmed cell death 1 ligand 2.	V-set domain-containing T-cell activation inhibitor 1.	0.512
SPTLC3	CEACAM19	ENSUMAP00000011359	ENSUMAP00000032146	Serine palmitoyltransferase long chain base subunit 3.	Carcinoembryonic antigen-related cell adhesion molecule 19.	0.573
SPTLC3	VTCN1	ENSUMAP00000011359	ENSUMAP00000005893	Serine palmitoyltransferase long chain base subunit 3.	V-set domain-containing T-cell activation inhibitor 1.	0.582
TMIGD2	TNFRSF18	ENSUMAP00000010131	ENSUMAP00000002791	Transmembrane and immunoglobulin domain-containing protein 2.	Tumor necrosis factor receptor superfamily member 18.	0.443
TMIGD2	TNFSF9	ENSUMAP00000010131	ENSUMAP00000015300	Transmembrane and immunoglobulin domain-containing protein 2.	Tumor necrosis factor ligand superfamily member 9; Belongs to the tumor necrosis factor family.	0.406
TMIGD2	VTCN1	ENSUMAP00000010131	ENSUMAP00000005893	Transmembrane and immunoglobulin domain-containing protein 2.	V-set domain-containing T-cell activation inhibitor 1.	0.513
TNFRSF18	CTLA4	ENSUMAP00000002791	ENSUMAP00000030761	Tumor necrosis factor receptor superfamily member 18.	Cytotoxic T-lymphocyte associated protein 4.	0.521
TNFRSF18	TMIGD2	ENSUMAP00000002791	ENSUMAP00000010131	Tumor necrosis factor receptor superfamily member 18.	Transmembrane and immunoglobulin domain-containing protein 2.	0.443
TNFRSF18	TNFSF9	ENSUMAP00000002791	ENSUMAP00000015300	Tumor necrosis factor receptor superfamily member 18.	Tumor necrosis factor ligand superfamily member 9; Belongs to the tumor necrosis factor family.	0.489
TNFRSF18	VTCN1	ENSUMAP00000002791	ENSUMAP00000005893	Tumor necrosis factor receptor superfamily member 18.	V-set domain-containing T-cell activation inhibitor 1.	0.495
TNFSF4	TNFSF9	ENSUMAP00000027508	ENSUMAP00000015300	Tumor necrosis factor ligand superfamily member 4; Belongs to the tumor necrosis factor family.	Tumor necrosis factor ligand superfamily member 9; Belongs to the tumor necrosis factor family.	0.586