STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC103677912ADP-ribosylation factor 3-like; Belongs to the small GTPase superfamily. Arf family. (247 aa)    
Predicted Functional Partners:
GBF1
LOW QUALITY PROTEIN: golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1.
    
 0.856
PLEKHA8
Pleckstrin homology domain-containing family A member 8-like.
   
 0.818
ITSN2
LOW QUALITY PROTEIN: intersectin-2.
    
 0.800
BBS7
Bardet-Biedl syndrome 7 protein.
   
 0.754
COPB1
Coatomer subunit beta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.
   
 0.733
BBS1
Bardet-Biedl syndrome 1 protein.
   
 0.724
PI4KB
Phosphatidylinositol 4-kinase beta isoform X4; Belongs to the PI3/PI4-kinase family.
    
 0.716
COPZ1
Coatomer subunit zeta; The zeta subunit may be involved in regulating the coat assembly and, hence, the rate of biosynthetic protein transport due to its association-dissociation properties with the coatomer complex.
   
 0.700
ITSN1
Intersectin-1 isoform X2.
    
 0.698
ENSUMAP00000027695
annotation not available
    
 0.698
Your Current Organism:
Ursus maritimus
NCBI taxonomy Id: 29073
Other names: Thalarctos maritimus, U. maritimus, polar bear, white bear
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.