STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC103679133Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4-like. (340 aa)    
Predicted Functional Partners:
TBX5
T-box transcription factor TBX5.
   
  
 0.734
KCNJ2
Potassium voltage-gated channel subfamily J member 2.
      
 0.731
KCNQ1
Potassium voltage-gated channel subfamily KQT member 1; Belongs to the potassium channel family.
    
 0.586
SYT2
Synaptotagmin 2.
    
 
 0.577
SYT1
Synaptotagmin-1 isoform X1.
    
 
 0.577
ATP2B3
Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium.
   
 
 0.548
HCN3
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3.
  
 
0.542
ASTN1
Astrotactin-1.
      
 0.540
CAV3
Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.
    
 
 0.537
KCNA5
LOW QUALITY PROTEIN: potassium voltage-gated channel subfamily A member 5; Belongs to the potassium channel family.
    
 0.532
Your Current Organism:
Ursus maritimus
NCBI taxonomy Id: 29073
Other names: Thalarctos maritimus, U. maritimus, polar bear, white bear
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