STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CLCN2Chloride channel protein. (859 aa)    
Predicted Functional Partners:
CYP21A2
Steroid 21-hydroxylase.
    
 
 0.731
SLC26A3
Chloride anion exchanger; Chloride/bicarbonate exchanger. Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
  
  
 0.719
OSTM1
Osteopetrosis-associated transmembrane protein 1.
   
 0.667
KCNK9
Potassium channel subfamily K member 9; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
      
 0.645
ATP2B3
Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium.
    
 
 0.644
BSND
Barttin.
   
 
 0.595
SLC31A1
High affinity copper uptake protein 1.
      
 0.585
KCNJ5
G protein-activated inward rectifier potassium channel 4.
   
  
 0.554
KCNJ13
Potassium voltage-gated channel subfamily J member 13.
   
  
 0.547
DPT
Dermatopontin.
      
 0.545
Your Current Organism:
Ursus maritimus
NCBI taxonomy Id: 29073
Other names: Thalarctos maritimus, U. maritimus, polar bear, white bear
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.