STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TMEM183ATransmembrane protein 183A. (367 aa)    
Predicted Functional Partners:
TMEM47
Transmembrane protein 47.
   
  
 0.645
RNF13
E3 ubiquitin-protein ligase RNF13 isoform X1.
      
 0.637
HSF2BP
Heat shock transcription factor 2 binding protein.
      
 0.637
TLK2
Serine/threonine-protein kinase tousled-like 2 isoform X1.
      
 0.636
ITSN2
LOW QUALITY PROTEIN: intersectin-2.
     
 0.617
TRMT12
tRNA wybutosine-synthesizing protein 2 homolog.
   
  
 0.531
RNF2
E3 ubiquitin-protein ligase RING2 isoform X1.
      
 0.518
RIMS2
Regulating synaptic membrane exocytosis protein 2 isoform X1.
     
 0.515
TMED4
Transmembrane emp24 domain-containing protein 4.
   
  
 0.512
INPP5A
Type I inositol 1,4,5-trisphosphate 5-phosphatase.
   
  
 0.507
Your Current Organism:
Ursus maritimus
NCBI taxonomy Id: 29073
Other names: Thalarctos maritimus, U. maritimus, polar bear, white bear
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.