STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ALCAMActivated leukocyte cell adhesion molecule. (583 aa)    
Predicted Functional Partners:
CD6
T-cell differentiation antigen CD6.
    
 0.986
NECTIN2
Nectin-2.
 
  
 0.549
AFDN
Afadin.
    
 0.524
CDCP1
CUB domain-containing protein 1.
  
  
 0.483
CASK
Peripheral plasma membrane protein CASK; Belongs to the MAGUK family.
    
 0.472
DLG5
Disks large homolog 5; Belongs to the MAGUK family.
    
 0.462
FRMD7
FERM domain-containing protein 7.
  
  
 0.419
ZAP70
Tyrosine-protein kinase.
    
 0.418
SYK
Tyrosine-protein kinase SYK; Belongs to the protein kinase superfamily. Tyr protein kinase family.
    
  0.415
ADAM17
Disintegrin and metalloproteinase domain-containing protein 17.
   
  
 0.413
Your Current Organism:
Ursus maritimus
NCBI taxonomy Id: 29073
Other names: Thalarctos maritimus, U. maritimus, polar bear, white bear
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.