STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CTBP1LOW QUALITY PROTEIN: C-terminal-binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (312 aa)    
Predicted Functional Partners:
RBBP8
DNA endonuclease RBBP8 isoform X1.
    
 
 0.958
APC
LOW QUALITY PROTEIN: adenomatous polyposis coli protein.
    
 0.952
PSAT1
Phosphoserine aminotransferase.
  
 0.948
CTNNB1
Catenin beta-1.
   
 0.924
ZNF217
Zinc finger protein 217.
    
 
 0.844
AGXT
Serine--pyruvate aminotransferase.
  
 
 0.810
TCF7L1
Transcription factor 7-like 1.
    
 0.784
FPGS
Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family.
  
 
 0.775
ZEB1
Zinc finger E-box-binding homeobox 1.
   
 
 0.772
GLDC
Glycine dehydrogenase (Decarboxylating), mitochondrial.
  
 
 0.772
Your Current Organism:
Ursus maritimus
NCBI taxonomy Id: 29073
Other names: Thalarctos maritimus, U. maritimus, polar bear, white bear
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.