STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RAD23AUV excision repair protein RAD23 homolog A. (351 aa)    
Predicted Functional Partners:
ATXN3
LOW QUALITY PROTEIN: ataxin-3.
    
 0.970
PSMD4
26S proteasome non-ATPase regulatory subunit 4.
   
 0.962
RAD23B
LOW QUALITY PROTEIN: UV excision repair protein RAD23 homolog B.
  
 
0.950
XPC
XPC complex subunit, DNA damage recognition and repair factor.
   
 0.939
NGLY1
peptide-N(4)-(N-acetyl-beta- glucosaminyl)asparagine amidase.
    
 0.931
RPS27A
ubiquitin-40S ribosomal protein S27a.
    
 0.904
CETN2
Centrin 2.
   
 0.894
PSMD2
26S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family.
   
 0.885
MYSM1
Histone H2A deubiquitinase MYSM1 isoform X1.
   
 0.874
PSMD14
26S proteasome non-ATPase regulatory subunit 14.
   
 0.870
Your Current Organism:
Ursus maritimus
NCBI taxonomy Id: 29073
Other names: Thalarctos maritimus, U. maritimus, polar bear, white bear
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.