STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PRPSAP2Phosphoribosyl pyrophosphate synthetase associated protein 2. (369 aa)    
Predicted Functional Partners:
PRPSAP1
Phosphoribosyl pyrophosphate synthase-associated protein 1.
  
 
0.875
PRPS1
Phosphoribosyl pyrophosphate synthetase 1-like 1.
  
0.819
PRPS2
Ribose-phosphate pyrophosphokinase 1.
  
0.811
BCKDHB
2-oxoisovalerate dehydrogenase subunit beta, mitochondrial isoform X1.
   
 0.733
PDHB
Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
   
 0.733
KARS1
Lysine--tRNA ligase.
   
 
 0.652
EPRS1
LOW QUALITY PROTEIN: bifunctional glutamate/proline--tRNA ligase.
  
 
 0.629
GART
Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family.
  
  
 0.593
IVNS1ABP
Influenza virus NS1A-binding protein.
    
 
 0.581
DLAT
Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
   
 0.572
Your Current Organism:
Ursus maritimus
NCBI taxonomy Id: 29073
Other names: Thalarctos maritimus, U. maritimus, polar bear, white bear
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.