STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TRAF3TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (568 aa)    
Predicted Functional Partners:
MAVS
LOW QUALITY PROTEIN: mitochondrial antiviral-signaling protein.
    
 0.999
TANK
TRAF family member-associated NF-kappa-B activator isoform X2.
    
 0.999
MAP3K14
Mitogen-activated protein kinase kinase kinase 14.
   
 0.999
TBK1
Serine/threonine-protein kinase TBK1.
   
 0.999
TRADD
Tumor necrosis factor receptor type 1-associated DEATH domain protein isoform X2.
    
 0.992
LTBR
Tumor necrosis factor receptor superfamily member 3 isoform X2.
    
 0.990
CD40
Tumor necrosis factor receptor superfamily member 5 isoform X5.
   
 0.986
TLR4
Toll-like receptor 4; Belongs to the Toll-like receptor family.
   
 0.985
TRAF6
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
   
0.985
BIRC2
Baculoviral IAP repeat-containing protein 2.
   
 0.982
Your Current Organism:
Ursus maritimus
NCBI taxonomy Id: 29073
Other names: Thalarctos maritimus, U. maritimus, polar bear, white bear
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.