node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AMD1 | DNMT1 | ENSUMAP00000035450 | ENSUMAP00000034894 | S-adenosylmethionine decarboxylase proenzyme. | DNA (cytosine-5)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. | 0.904 |
AMD1 | DNMT3B | ENSUMAP00000035450 | ENSUMAP00000033540 | S-adenosylmethionine decarboxylase proenzyme. | DNA (Cytosine-5)-methyltransferase 3B isoform X1; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. | 0.900 |
AMD1 | MAT1A | ENSUMAP00000035450 | ENSUMAP00000019285 | S-adenosylmethionine decarboxylase proenzyme. | S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP. | 0.950 |
AMD1 | MAT2A | ENSUMAP00000035450 | ENSUMAP00000008500 | S-adenosylmethionine decarboxylase proenzyme. | S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP. | 0.944 |
AMD1 | MAT2B | ENSUMAP00000035450 | ENSUMAP00000034435 | S-adenosylmethionine decarboxylase proenzyme. | Methionine adenosyltransferase 2 subunit beta; Regulatory subunit of S-adenosylmethionine synthetase 2, an enzyme that catalyzes the formation of S-adenosylmethionine from methionine and ATP. Regulates MAT2A catalytic activity by changing its kinetic properties, increasing its affinity for L-methionine. | 0.921 |
AMD1 | TAT | ENSUMAP00000035450 | ENSUMAP00000024686 | S-adenosylmethionine decarboxylase proenzyme. | Tyrosine aminotransferase; Transaminase involved in tyrosine breakdown. Converts tyrosine to p-hydroxyphenylpyruvate. | 0.400 |
BHMT | BHMT2 | ENSUMAP00000002212 | ENSUMAP00000002204 | Betaine--homocysteine S-methyltransferase 1; Involved in the regulation of homocysteine metabolism. | S-methylmethionine--homocysteine S-methyltransferase BHMT2; Involved in the regulation of homocysteine metabolism. | 0.901 |
BHMT | LOC103670918 | ENSUMAP00000002212 | ENSUMAP00000033803 | Betaine--homocysteine S-methyltransferase 1; Involved in the regulation of homocysteine metabolism. | Amine oxidase. | 0.906 |
BHMT | MAT1A | ENSUMAP00000002212 | ENSUMAP00000019285 | Betaine--homocysteine S-methyltransferase 1; Involved in the regulation of homocysteine metabolism. | S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP. | 0.981 |
BHMT | MAT2A | ENSUMAP00000002212 | ENSUMAP00000008500 | Betaine--homocysteine S-methyltransferase 1; Involved in the regulation of homocysteine metabolism. | S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP. | 0.969 |
BHMT | MAT2B | ENSUMAP00000002212 | ENSUMAP00000034435 | Betaine--homocysteine S-methyltransferase 1; Involved in the regulation of homocysteine metabolism. | Methionine adenosyltransferase 2 subunit beta; Regulatory subunit of S-adenosylmethionine synthetase 2, an enzyme that catalyzes the formation of S-adenosylmethionine from methionine and ATP. Regulates MAT2A catalytic activity by changing its kinetic properties, increasing its affinity for L-methionine. | 0.939 |
BHMT | MTR | ENSUMAP00000002212 | ENSUMAP00000018291 | Betaine--homocysteine S-methyltransferase 1; Involved in the regulation of homocysteine metabolism. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.935 |
BHMT | TAT | ENSUMAP00000002212 | ENSUMAP00000024686 | Betaine--homocysteine S-methyltransferase 1; Involved in the regulation of homocysteine metabolism. | Tyrosine aminotransferase; Transaminase involved in tyrosine breakdown. Converts tyrosine to p-hydroxyphenylpyruvate. | 0.929 |
BHMT2 | BHMT | ENSUMAP00000002204 | ENSUMAP00000002212 | S-methylmethionine--homocysteine S-methyltransferase BHMT2; Involved in the regulation of homocysteine metabolism. | Betaine--homocysteine S-methyltransferase 1; Involved in the regulation of homocysteine metabolism. | 0.901 |
BHMT2 | LOC103670918 | ENSUMAP00000002204 | ENSUMAP00000033803 | S-methylmethionine--homocysteine S-methyltransferase BHMT2; Involved in the regulation of homocysteine metabolism. | Amine oxidase. | 0.906 |
BHMT2 | MAT1A | ENSUMAP00000002204 | ENSUMAP00000019285 | S-methylmethionine--homocysteine S-methyltransferase BHMT2; Involved in the regulation of homocysteine metabolism. | S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP. | 0.981 |
BHMT2 | MAT2A | ENSUMAP00000002204 | ENSUMAP00000008500 | S-methylmethionine--homocysteine S-methyltransferase BHMT2; Involved in the regulation of homocysteine metabolism. | S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP. | 0.969 |
BHMT2 | MAT2B | ENSUMAP00000002204 | ENSUMAP00000034435 | S-methylmethionine--homocysteine S-methyltransferase BHMT2; Involved in the regulation of homocysteine metabolism. | Methionine adenosyltransferase 2 subunit beta; Regulatory subunit of S-adenosylmethionine synthetase 2, an enzyme that catalyzes the formation of S-adenosylmethionine from methionine and ATP. Regulates MAT2A catalytic activity by changing its kinetic properties, increasing its affinity for L-methionine. | 0.939 |
BHMT2 | MTR | ENSUMAP00000002204 | ENSUMAP00000018291 | S-methylmethionine--homocysteine S-methyltransferase BHMT2; Involved in the regulation of homocysteine metabolism. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.952 |
BHMT2 | TAT | ENSUMAP00000002204 | ENSUMAP00000024686 | S-methylmethionine--homocysteine S-methyltransferase BHMT2; Involved in the regulation of homocysteine metabolism. | Tyrosine aminotransferase; Transaminase involved in tyrosine breakdown. Converts tyrosine to p-hydroxyphenylpyruvate. | 0.929 |