STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DHHDesert hedgehog protein. (372 aa)    
Predicted Functional Partners:
PTCH1
Protein patched homolog 1.
   
 0.998
HHIP
Hedgehog-interacting protein isoform X1.
    
 0.998
PTCH2
LOW QUALITY PROTEIN: protein patched homolog 2.
   
 0.995
CDON
Cell adhesion molecule-related/down-regulated by oncogenes isoform X1.
    
 0.993
IHH
Indian hedgehog protein.
  
  
0.979
LRP2
Low-density lipoprotein receptor-related protein 2.
     
 0.909
HHAT
Protein-cysteine N-palmitoyltransferase HHAT; Belongs to the membrane-bound acyltransferase family.
   
 0.902
BOC
LOW QUALITY PROTEIN: brother of CDO.
    
 0.893
DISP1
Protein dispatched homolog 1 isoform X1.
   
 0.879
SMO
Smoothened homolog; Belongs to the G-protein coupled receptor Fz/Smo family.
   
 0.866
Your Current Organism:
Ursus maritimus
NCBI taxonomy Id: 29073
Other names: Thalarctos maritimus, U. maritimus, polar bear, white bear
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.