STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ATF5LOW QUALITY PROTEIN: cyclic AMP-dependent transcription factor ATF-5. (248 aa)    
Predicted Functional Partners:
CEBPG
CCAAT enhancer binding protein gamma.
   
 0.736
ASNS
Asparagine synthetase [glutamine-hydrolyzing].
   
 
 0.639
DDIT3
DNA damage-inducible transcript 3 protein; Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer- binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression [...]
   
 0.637
ATF3
Cyclic AMP-dependent transcription factor ATF-3.
    
 0.589
TRIB3
Tribbles homolog 3.
   
 0.583
NAT14
N-acetyltransferase 14 (putative).
  
     0.519
CEBPE
CCAAT/enhancer-binding protein.
   
 0.515
CLPP
ATP-dependent Clp protease proteolytic subunit.
      
 0.512
XBP1
LOW QUALITY PROTEIN: X-box-binding protein 1.
   
 
 0.509
NDUFAF6
NADH dehydrogenase (Ubiquinone) complex I, assembly factor 6.
      
 0.504
Your Current Organism:
Ursus maritimus
NCBI taxonomy Id: 29073
Other names: Thalarctos maritimus, U. maritimus, polar bear, white bear
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.