STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LTBRTumor necrosis factor receptor superfamily member 3 isoform X2. (421 aa)    
Predicted Functional Partners:
TRAF3
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
    
 0.990
LTA
Lymphotoxin-alpha; Belongs to the tumor necrosis factor family.
   
 0.989
TRAF5
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
    
 0.973
MAP3K14
Mitogen-activated protein kinase kinase kinase 14.
   
 0.961
TNFSF14
Tumor necrosis factor ligand superfamily member 14; Belongs to the tumor necrosis factor family.
   
 0.956
CD40LG
CD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching.
   
 0.834
TNFSF18
Tumor necrosis factor ligand superfamily member 18.
   
 0.760
TNFSF11
Tumor necrosis factor ligand superfamily member 11; Belongs to the tumor necrosis factor family.
   
 0.759
TNFRSF1A
LOW QUALITY PROTEIN: tumor necrosis factor receptor superfamily member 1A.
   
  
0.738
TRAF2
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
    
 0.735
Your Current Organism:
Ursus maritimus
NCBI taxonomy Id: 29073
Other names: Thalarctos maritimus, U. maritimus, polar bear, white bear
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