STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
UNC5BNetrin receptor UNC5B. (913 aa)    
Predicted Functional Partners:
NEO1
Neogenin.
    
 0.846
FLRT3
Fibronectin leucine rich transmembrane protein 3.
    
 0.810
ROBO4
LOW QUALITY PROTEIN: roundabout homolog 4.
     
0.779
NTN4
Netrin-4 isoform X1.
      
 0.646
AGAP2
LOW QUALITY PROTEIN: arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2.
    
 0.580
DLL4
Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.
    
 0.556
ESM1
Endothelial cell-specific molecule 1 isoform X1.
      
 0.532
CASP3
Caspase-3 isoform X1; Belongs to the peptidase C14A family.
     
 0.532
DSCAML1
Down syndrome cell adhesion molecule-like protein 1.
    
 0.519
FAIM2
Protein lifeguard 2; Belongs to the BI1 family.
      
 0.519
Your Current Organism:
Ursus maritimus
NCBI taxonomy Id: 29073
Other names: Thalarctos maritimus, U. maritimus, polar bear, white bear
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.