STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PHC2Polyhomeotic-like protein 2 isoform X2. (805 aa)    
Predicted Functional Partners:
CBX8
Chromobox protein homolog 8.
    
 0.835
CBX7
Chromobox protein homolog 7.
    
 0.758
RING1
E3 ubiquitin-protein ligase RING1.
    
 0.743
RNF2
E3 ubiquitin-protein ligase RING2 isoform X1.
    
 0.743
BMI1
Polycomb complex protein BMI-1.
    
 0.736
PCGF2
Polycomb group RING finger protein 2 isoform X1.
    
 0.736
SCML2
Sex comb on midleg-like protein 2.
    
0.675
EED
Polycomb protein EED.
    
 0.632
PCGF5
Polycomb group RING finger protein 5 isoform X3.
    
 0.612
PCGF6
Polycomb group RING finger protein 6.
    
 0.598
Your Current Organism:
Ursus maritimus
NCBI taxonomy Id: 29073
Other names: Thalarctos maritimus, U. maritimus, polar bear, white bear
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.