STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LIMS2LIM and senescent cell antigen-like-containing domain protein; Adapter protein in a cytoplasmic complex linking beta- integrins to the actin cytoskeleton, bridges the complex to cell surface receptor tyrosine kinases and growth factor receptors. (339 aa)    
Predicted Functional Partners:
ILK
Integrin-linked protein kinase.
   
 0.948
RSU1
Ras Suppressor protein 1.
   
 0.946
PARVA
Alpha-parvin isoform X2.
   
 0.873
PARVB
Beta-parvin isoform X1.
   
 0.873
PARVG
LOW QUALITY PROTEIN: gamma-parvin.
  
 0.774
NAALADL2
Inactive N-acetylated-alpha-linked acidic dipeptidase-like protein 2 isoform X1.
      
 0.746
NCK2
Cytoplasmic protein.
    
 
 0.676
PIDD1
LOW QUALITY PROTEIN: p53-induced death domain-containing protein 1.
    
 0.647
ST8SIA6
Alpha-2,8-sialyltransferase 8F; Belongs to the glycosyltransferase 29 family.
      
 0.635
SORBS1
Sorbin and SH3 domain-containing protein 1 isoform X5.
   
  
 0.594
Your Current Organism:
Ursus maritimus
NCBI taxonomy Id: 29073
Other names: Thalarctos maritimus, U. maritimus, polar bear, white bear
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