STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
IGFBP7Insulin-like growth factor-binding protein 7. (188 aa)    
Predicted Functional Partners:
IGF1
Insulin-like growth factor I isoform X1.
    
 
 0.838
P4HB
LOW QUALITY PROTEIN: protein disulfide-isomerase.
      
 0.796
IGFBP3
Insulin-like growth factor-binding protein 3.
      
 0.748
PCOLCE
Procollagen C-endopeptidase enhancer 1.
   
  
 0.734
FREM3
LOW QUALITY PROTEIN: FRAS1-related extracellular matrix protein 3.
      
 0.596
INS-IGF2
Insulin, isoform 2-like; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.
    
 
 0.590
ST3GAL1
CMP-N-acetylneuraminate-beta-galactosamide- alpha-2,3-sialyltransferase 1; Belongs to the glycosyltransferase 29 family.
   
  
 0.535
FBXO47
F-box only protein 47 isoform X1.
   
    0.531
PROKR2
Prokineticin receptor 2; Belongs to the G-protein coupled receptor 1 family.
      
 0.530
MTRR
5-methyltetrahydrofolate-homocysteine methyltransferase reductase.
      
 0.530
Your Current Organism:
Ursus maritimus
NCBI taxonomy Id: 29073
Other names: Thalarctos maritimus, U. maritimus, polar bear, white bear
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