STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SPTLC3Serine palmitoyltransferase long chain base subunit 3. (552 aa)    
Predicted Functional Partners:
SPTLC1
Serine palmitoyltransferase long chain base subunit 1.
  
0.999
KDSR
3-ketodihydrosphingosine reductase; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
     
 0.986
SPTSSB
Serine palmitoyltransferase small subunit B.
    
 0.916
SHMT1-2
Serine hydroxymethyltransferase 1.
  
 
 0.833
SHMT2
Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family.
  
 
 0.833
CBS
Cystathionine beta-synthase.
    
 0.833
SDS
L-serine dehydratase/L-threonine deaminase.
   
 0.830
SDSL
Serine dehydratase-like isoform X4.
   
 0.826
PSPH
Phosphoserine phosphatase.
    
 0.815
SORD
Sorbitol dehydrogenase.
 
 
 0.753
Your Current Organism:
Ursus maritimus
NCBI taxonomy Id: 29073
Other names: Thalarctos maritimus, U. maritimus, polar bear, white bear
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.