STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NPC2NPC intracellular cholesterol transporter 2. (149 aa)    
Predicted Functional Partners:
NPC1
Niemann-Pick C1 protein.
   
 0.998
NPC1L1
LOW QUALITY PROTEIN: Niemann-Pick C1-like protein 1.
   
 0.915
SCAP
Sterol regulatory element-binding protein cleavage-activating protein.
   
 0.822
APOB
Apolipoprotein B-100.
     
 0.680
CD52
CD52 molecule.
      
 0.600
ENSUMAP00000035008
annotation not available
      
 0.600
GM2A
Ganglioside GM2 activator-like.
   
  
 0.557
ATP7B
Copper-transporting ATPase 2.
      
 0.556
LAMP1
Lysosome-associated membrane glycoprotein 1.
   
  
 0.549
ARSA
Arylsulfatase A isoform X1.
   
  
 0.463
Your Current Organism:
Ursus maritimus
NCBI taxonomy Id: 29073
Other names: Thalarctos maritimus, U. maritimus, polar bear, white bear
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.