STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PLK1Serine/threonine-protein kinase PLK. (573 aa)    
Predicted Functional Partners:
CDC20
Cell division cycle protein 20 homolog.
   
 0.999
CDK1
Cyclin-dependent kinase 1; Belongs to the protein kinase superfamily.
   
0.998
PKMYT1
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase isoform X1; Belongs to the protein kinase superfamily.
   
0.995
PLK4
Serine/threonine-protein kinase PLK4.
   
0.995
CCNB1
LOW QUALITY PROTEIN: G2/mitotic-specific cyclin-B1; Belongs to the cyclin family.
   
 0.993
ESPL1
Separin.
   
 0.993
CCNB2
G2/mitotic-specific cyclin-B2; Belongs to the cyclin family.
   
 0.993
BUB1
Mitotic checkpoint serine/threonine-protein kinase BUB1.
   
 0.987
FOXM1
Forkhead box protein M1.
   
 0.987
KIF2C
Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
   
 0.986
Your Current Organism:
Ursus maritimus
NCBI taxonomy Id: 29073
Other names: Thalarctos maritimus, U. maritimus, polar bear, white bear
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.