STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SGSM2Small G protein signaling modulator 2. (1127 aa)    
Predicted Functional Partners:
KCNK4
Potassium channel subfamily K member 4; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
      
 0.776
PEX1
Peroxisome biogenesis factor 1 isoform X1.
     
 0.773
WDR45B
WD repeat domain phosphoinositide-interacting protein 3.
      
 0.635
PAFAH1B1
Platelet-activating factor acetylhydrolase IB subunit alpha; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the peripheral transport of microtubule fragments and the coupling of the nucleus and centrosome. Required during brain development for the proliferation of neuronal precursors and the migration of newly formed neurons from the ven [...]
      
 0.598
SMG6
Telomerase-binding protein EST1A isoform X1.
   
  
 0.598
RABGEF1
Rab5 GDP/GTP exchange factor isoform X2.
     
 0.552
SGSM3
Small G protein signaling modulator 3 isoform X2.
      
 0.523
CUEDC1
CUE domain-containing protein 1.
      
 0.504
TRARG1
Tumor suppressor candidate 5 isoform X1.
      
 0.457
KIF19
Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
      
 0.455
Your Current Organism:
Ursus maritimus
NCBI taxonomy Id: 29073
Other names: Thalarctos maritimus, U. maritimus, polar bear, white bear
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.