STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
IQGAP1Ras GTPase-activating-like protein IQGAP1. (1677 aa)    
Predicted Functional Partners:
CDC42
Cell division control protein 42 homolog isoform X1.
   
 0.995
CTNNB1
Catenin beta-1.
   
 0.990
MAPK1
Mitogen-activated protein kinase.
   
 0.958
ENSUMAP00000021933
annotation not available
   
 0.958
MAPK3
Mitogen-activated protein kinase.
   
 0.956
IQGAP3
Ras GTPase-activating-like protein IQGAP3.
  
  
0.940
ACTG1
LOW QUALITY PROTEIN: actin, cytoplasmic 2.
    
 0.934
CALML5
Calmodulin-like protein 5.
    
 0.897
BRAF
Serine/threonine-protein kinase B-raf.
    
 0.884
CDH1
Cadherin-1; Cadherins are calcium-dependent cell adhesion proteins.
    
 0.884
Your Current Organism:
Ursus maritimus
NCBI taxonomy Id: 29073
Other names: Thalarctos maritimus, U. maritimus, polar bear, white bear
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.