STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HECTD4Probable E3 ubiquitin-protein ligase HECTD4. (4290 aa)    
Predicted Functional Partners:
RANBP2
E3 SUMO-protein ligase RanBP2.
   
 0.542
ND4
NADH-ubiquinone oxidoreductase chain 4; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
    
 
 0.480
ZFAND4
AN1-type zinc finger protein 4 isoform X1.
    
 0.473
EVC
Ellis-van Creveld syndrome protein.
   
 0.472
GGA3
ADP-ribosylation factor-binding protein GGA3 isoform X2.
   
 
 0.457
ENSUMAP00000001541
annotation not available
    
 0.446
ADGRB2
Brain-specific angiogenesis inhibitor 2; Belongs to the G-protein coupled receptor 2 family.
    
 0.446
ADGRB3
Brain-specific angiogenesis inhibitor 3; Belongs to the G-protein coupled receptor 2 family.
    
 0.446
ADGRD1
Probable G-protein coupled receptor 133; Belongs to the G-protein coupled receptor 2 family.
    
 0.446
RAN
GTP-binding nuclear protein Ran; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family.
    
 0.446
Your Current Organism:
Ursus maritimus
NCBI taxonomy Id: 29073
Other names: Thalarctos maritimus, U. maritimus, polar bear, white bear
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.