STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ARHGEF17Rho guanine nucleotide exchange factor 17. (1878 aa)    
Predicted Functional Partners:
NUAK2
LOW QUALITY PROTEIN: NUAK family SNF1-like kinase 2.
      
 0.642
TBRG1
Transforming growth factor beta regulator 1.
   
  
 0.608
TUBGCP2
Gamma-tubulin complex component; Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome; Belongs to the TUBGCP family.
      
 0.604
CROCC2
Putative ciliary rootlet coiled-coil protein-like 3 protein.
    
 
 0.603
ZNF512B
Zinc finger protein 512B.
    
 
 0.597
ARHGEF40
LOW QUALITY PROTEIN: rho guanine nucleotide exchange factor 40.
   
 
 0.586
GDPD5
LOW QUALITY PROTEIN: glycerophosphodiester phosphodiesterase domain-containing protein 5.
      
 0.564
PTPN14
Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class subfamily.
   
  
 0.548
ARHGAP24
Rho GTPase-activating protein 24 isoform X1.
   
  
 0.540
ACER3
Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid.
      
 0.524
Your Current Organism:
Ursus maritimus
NCBI taxonomy Id: 29073
Other names: Thalarctos maritimus, U. maritimus, polar bear, white bear
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.