node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CDC45 | CDC6 | ENSUMAP00000009200 | ENSUMAP00000024485 | Cell division control protein 45 homolog. | Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. | 0.958 |
CDC45 | CDC7 | ENSUMAP00000009200 | ENSUMAP00000001376 | Cell division control protein 45 homolog. | LOW QUALITY PROTEIN: cell division cycle 7-related protein kinase. | 0.882 |
CDC45 | CDT1 | ENSUMAP00000009200 | ENSUMAP00000011034 | Cell division control protein 45 homolog. | DNA replication factor Cdt1. | 0.974 |
CDC45 | MCM2 | ENSUMAP00000009200 | ENSUMAP00000020235 | Cell division control protein 45 homolog. | DNA helicase; Belongs to the MCM family. | 0.998 |
CDC45 | MCM3 | ENSUMAP00000009200 | ENSUMAP00000005511 | Cell division control protein 45 homolog. | DNA helicase; Belongs to the MCM family. | 0.997 |
CDC45 | MCM4 | ENSUMAP00000009200 | ENSUMAP00000008557 | Cell division control protein 45 homolog. | DNA helicase; Belongs to the MCM family. | 0.999 |
CDC45 | MCM5 | ENSUMAP00000009200 | ENSUMAP00000023262 | Cell division control protein 45 homolog. | DNA helicase; Belongs to the MCM family. | 0.998 |
CDC45 | MCM6 | ENSUMAP00000009200 | ENSUMAP00000007710 | Cell division control protein 45 homolog. | DNA helicase; Belongs to the MCM family. | 0.998 |
CDC45 | MCM7 | ENSUMAP00000009200 | ENSUMAP00000014080 | Cell division control protein 45 homolog. | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | 0.996 |
CDC45 | ORC2 | ENSUMAP00000009200 | ENSUMAP00000029746 | Cell division control protein 45 homolog. | Origin recognition complex subunit 2 isoform X2. | 0.926 |
CDC6 | CDC45 | ENSUMAP00000024485 | ENSUMAP00000009200 | Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. | Cell division control protein 45 homolog. | 0.958 |
CDC6 | CDC7 | ENSUMAP00000024485 | ENSUMAP00000001376 | Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. | LOW QUALITY PROTEIN: cell division cycle 7-related protein kinase. | 0.923 |
CDC6 | CDT1 | ENSUMAP00000024485 | ENSUMAP00000011034 | Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. | DNA replication factor Cdt1. | 0.999 |
CDC6 | MCM2 | ENSUMAP00000024485 | ENSUMAP00000020235 | Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. | DNA helicase; Belongs to the MCM family. | 0.998 |
CDC6 | MCM3 | ENSUMAP00000024485 | ENSUMAP00000005511 | Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. | DNA helicase; Belongs to the MCM family. | 0.998 |
CDC6 | MCM4 | ENSUMAP00000024485 | ENSUMAP00000008557 | Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. | DNA helicase; Belongs to the MCM family. | 0.999 |
CDC6 | MCM5 | ENSUMAP00000024485 | ENSUMAP00000023262 | Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. | DNA helicase; Belongs to the MCM family. | 0.998 |
CDC6 | MCM6 | ENSUMAP00000024485 | ENSUMAP00000007710 | Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. | DNA helicase; Belongs to the MCM family. | 0.998 |
CDC6 | MCM7 | ENSUMAP00000024485 | ENSUMAP00000014080 | Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | 0.998 |
CDC6 | ORC2 | ENSUMAP00000024485 | ENSUMAP00000029746 | Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. | Origin recognition complex subunit 2 isoform X2. | 0.999 |