PPME1 protein (Ursus maritimus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

PPME1

Protein phosphatase methylesterase 1; Demethylates proteins that have been reversibly carboxymethylated. (356 aa)

Predicted Functional Partners:

PPP2R1B

0.948

PPP2CB

0.940

PPP2CA

0.940

PPP2R1A

0.939

ABHD17B

0.790

LCMT1

0.760

RBBP9

0.741

CIP2A

0.737

LOC103670942

0.700

PPP4R4

0.700

Your Current Organism:

Ursus maritimus

NCBI taxonomy Id: 29073
Other names: Thalarctos maritimus, U. maritimus, polar bear, white bear

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ABHD17B	PPME1	ENSUMAP00000030332	ENSUMAP00000014390	Alpha/beta hydrolase domain-containing protein 17B isoform X1.	Protein phosphatase methylesterase 1; Demethylates proteins that have been reversibly carboxymethylated.	0.790
ABHD17B	RBBP9	ENSUMAP00000030332	ENSUMAP00000034655	Alpha/beta hydrolase domain-containing protein 17B isoform X1.	RB binding protein 9, serine hydrolase.	0.818
CIP2A	LCMT1	ENSUMAP00000006718	ENSUMAP00000008042	Protein CIP2A.	Leucine carboxyl methyltransferase 1; Methylates the carboxyl group of the C-terminal leucine residue of protein phosphatase 2A catalytic subunits to form alpha- leucine ester residues; Belongs to the methyltransferase superfamily. LCMT family.	0.491
CIP2A	PPME1	ENSUMAP00000006718	ENSUMAP00000014390	Protein CIP2A.	Protein phosphatase methylesterase 1; Demethylates proteins that have been reversibly carboxymethylated.	0.737
LCMT1	CIP2A	ENSUMAP00000008042	ENSUMAP00000006718	Leucine carboxyl methyltransferase 1; Methylates the carboxyl group of the C-terminal leucine residue of protein phosphatase 2A catalytic subunits to form alpha- leucine ester residues; Belongs to the methyltransferase superfamily. LCMT family.	Protein CIP2A.	0.491
LCMT1	LOC103670942	ENSUMAP00000008042	ENSUMAP00000002953	Leucine carboxyl methyltransferase 1; Methylates the carboxyl group of the C-terminal leucine residue of protein phosphatase 2A catalytic subunits to form alpha- leucine ester residues; Belongs to the methyltransferase superfamily. LCMT family.	Putative serine/threonine-protein phosphatase 4 regulatory subunit 1-like.	0.545
LCMT1	PPME1	ENSUMAP00000008042	ENSUMAP00000014390	Leucine carboxyl methyltransferase 1; Methylates the carboxyl group of the C-terminal leucine residue of protein phosphatase 2A catalytic subunits to form alpha- leucine ester residues; Belongs to the methyltransferase superfamily. LCMT family.	Protein phosphatase methylesterase 1; Demethylates proteins that have been reversibly carboxymethylated.	0.760
LCMT1	PPP2CA	ENSUMAP00000008042	ENSUMAP00000024435	Leucine carboxyl methyltransferase 1; Methylates the carboxyl group of the C-terminal leucine residue of protein phosphatase 2A catalytic subunits to form alpha- leucine ester residues; Belongs to the methyltransferase superfamily. LCMT family.	Protein phosphatase 2 catalytic subunit alpha.	0.897
LCMT1	PPP2CB	ENSUMAP00000008042	ENSUMAP00000009538	Leucine carboxyl methyltransferase 1; Methylates the carboxyl group of the C-terminal leucine residue of protein phosphatase 2A catalytic subunits to form alpha- leucine ester residues; Belongs to the methyltransferase superfamily. LCMT family.	Serine/threonine-protein phosphatase.	0.897
LCMT1	PPP2R1A	ENSUMAP00000008042	ENSUMAP00000014142	Leucine carboxyl methyltransferase 1; Methylates the carboxyl group of the C-terminal leucine residue of protein phosphatase 2A catalytic subunits to form alpha- leucine ester residues; Belongs to the methyltransferase superfamily. LCMT family.	Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform.	0.779
LCMT1	PPP2R1B	ENSUMAP00000008042	ENSUMAP00000009407	Leucine carboxyl methyltransferase 1; Methylates the carboxyl group of the C-terminal leucine residue of protein phosphatase 2A catalytic subunits to form alpha- leucine ester residues; Belongs to the methyltransferase superfamily. LCMT family.	Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform.	0.701
LCMT1	PPP4R4	ENSUMAP00000008042	ENSUMAP00000005659	Leucine carboxyl methyltransferase 1; Methylates the carboxyl group of the C-terminal leucine residue of protein phosphatase 2A catalytic subunits to form alpha- leucine ester residues; Belongs to the methyltransferase superfamily. LCMT family.	Serine/threonine-protein phosphatase 4 regulatory subunit 4.	0.545
LOC103670942	LCMT1	ENSUMAP00000002953	ENSUMAP00000008042	Putative serine/threonine-protein phosphatase 4 regulatory subunit 1-like.	Leucine carboxyl methyltransferase 1; Methylates the carboxyl group of the C-terminal leucine residue of protein phosphatase 2A catalytic subunits to form alpha- leucine ester residues; Belongs to the methyltransferase superfamily. LCMT family.	0.545
LOC103670942	PPME1	ENSUMAP00000002953	ENSUMAP00000014390	Putative serine/threonine-protein phosphatase 4 regulatory subunit 1-like.	Protein phosphatase methylesterase 1; Demethylates proteins that have been reversibly carboxymethylated.	0.700
LOC103670942	PPP2CA	ENSUMAP00000002953	ENSUMAP00000024435	Putative serine/threonine-protein phosphatase 4 regulatory subunit 1-like.	Protein phosphatase 2 catalytic subunit alpha.	0.711
LOC103670942	PPP2CB	ENSUMAP00000002953	ENSUMAP00000009538	Putative serine/threonine-protein phosphatase 4 regulatory subunit 1-like.	Serine/threonine-protein phosphatase.	0.711
LOC103670942	PPP4R4	ENSUMAP00000002953	ENSUMAP00000005659	Putative serine/threonine-protein phosphatase 4 regulatory subunit 1-like.	Serine/threonine-protein phosphatase 4 regulatory subunit 4.	0.441
PPME1	ABHD17B	ENSUMAP00000014390	ENSUMAP00000030332	Protein phosphatase methylesterase 1; Demethylates proteins that have been reversibly carboxymethylated.	Alpha/beta hydrolase domain-containing protein 17B isoform X1.	0.790
PPME1	CIP2A	ENSUMAP00000014390	ENSUMAP00000006718	Protein phosphatase methylesterase 1; Demethylates proteins that have been reversibly carboxymethylated.	Protein CIP2A.	0.737
PPME1	LCMT1	ENSUMAP00000014390	ENSUMAP00000008042	Protein phosphatase methylesterase 1; Demethylates proteins that have been reversibly carboxymethylated.	Leucine carboxyl methyltransferase 1; Methylates the carboxyl group of the C-terminal leucine residue of protein phosphatase 2A catalytic subunits to form alpha- leucine ester residues; Belongs to the methyltransferase superfamily. LCMT family.	0.760