STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FBXW8F-box/WD repeat-containing protein 8. (553 aa)    
Predicted Functional Partners:
SKP1
S-phase kinase-associated protein 1; Belongs to the SKP1 family.
    
 0.995
RBX1
E3 ubiquitin-protein ligase RBX1.
    
 0.989
CUL7
LOW QUALITY PROTEIN: cullin-7; Belongs to the cullin family.
   
 0.976
CUL7-2
Cullin 7.
   
 0.976
GLMN
Glomulin, FKBP associated protein.
    
 0.953
CUL1
Cullin-1; Belongs to the cullin family.
    
 0.847
FBXL12
F-box/LRR-repeat protein 12.
    
 0.767
KCTD3
BTB/POZ domain-containing protein KCTD3.
      
 0.748
FBXL5
F-box/LRR-repeat protein 5.
     
 0.741
UBE4B
Ubiquitin conjugation factor E4 B.
   
  
 0.702
Your Current Organism:
Ursus maritimus
NCBI taxonomy Id: 29073
Other names: Thalarctos maritimus, U. maritimus, polar bear, white bear
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.