STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SESN2Sestrin-2. (464 aa)    
Predicted Functional Partners:
MIOS
WD repeat-containing protein mio isoform X2.
    
 0.993
WDR24
WD repeat-containing protein 24-like.
    
 0.987
DEPDC5
DEP domain-containing protein 5.
    
 0.979
SEC13
SEC13 homolog, nuclear pore and COPII coat complex component; Belongs to the WD repeat SEC13 family.
    
 0.967
PRKAA2
Non-specific serine/threonine protein kinase.
     
 0.963
PRKAB1
Protein kinase AMP-activated non-catalytic subunit beta 1.
     
 0.960
SEH1L
Nucleoporin SEH1 isoform X1; Belongs to the WD repeat SEC13 family.
     
 0.952
PRKAG3
5'-AMP-activated protein kinase subunit gamma-3.
   
 
 0.950
PRKAG1
5'-AMP-activated protein kinase subunit gamma-1 isoform X2.
   
 
 0.942
SESN3
Sestrin-3.
  
  
0.941
Your Current Organism:
Ursus maritimus
NCBI taxonomy Id: 29073
Other names: Thalarctos maritimus, U. maritimus, polar bear, white bear
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.