STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EHD4EH domain-containing protein 4; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (539 aa)    
Predicted Functional Partners:
RBSN
Rabenosyn, RAB effector.
    
 0.719
CDH23
Cadherin-23.
   
  
 0.709
MICALL1
LOW QUALITY PROTEIN: MICAL-like protein 1.
    
 
 0.632
ENPP4
Ectonucleotide pyrophosphatase/phosphodiesterase 4.
      
 0.600
SPART
Spartin isoform X2.
      
 0.518
EHBP1
EH domain-binding protein 1 isoform X1.
   
 
 0.492
ANKFY1
Ankyrin repeat and FYVE domain-containing protein 1.
    
 
 0.482
EIF3L
Eukaryotic translation initiation factor 3 subunit L; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF- 2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribos [...]
    
 
 0.466
ERN1
Serine/threonine-protein kinase/endoribonuclease IRE1.
    
 
 0.458
TUFT1
Tuftelin isoform X1.
      
 0.457
Your Current Organism:
Ursus maritimus
NCBI taxonomy Id: 29073
Other names: Thalarctos maritimus, U. maritimus, polar bear, white bear
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.