STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BBS1Bardet-Biedl syndrome 1 protein. (602 aa)    
Predicted Functional Partners:
BBS2
Bardet-Biedl syndrome 2 protein homolog.
   
 0.999
BBS9
Protein PTHB1 isoform X1.
    
 0.999
BBS7
Bardet-Biedl syndrome 7 protein.
   
 0.999
TTC8
Tetratricopeptide repeat protein 8 isoform X1.
   
 0.999
BBS4
Bardet-Biedl syndrome 4 protein isoform X2.
   
 0.999
BBS5
Bardet-Biedl syndrome 5 protein homolog; The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function. This ciliogenic function is mediated in part by the Rab8 GDP/GTP exchange factor, which localizes to the basal body and contacts the BBSome. Rab8(GTP) enters the primary cilium and promotes extension of the ciliary membrane. Firstly the BBSome associates with the ciliary membrane and binds to RAB3IP/Rabin8, the gua [...]
  
 
 0.999
BBIP1
LOW QUALITY PROTEIN: BBSome-interacting protein 1.
    
 0.996
KLHL41
Kelch like family member 41.
    
 0.966
ENSUMAP00000010549
annotation not available
   
 0.933
LZTFL1
Leucine zipper transcription factor-like protein 1 isoform X1.
   
 0.875
Your Current Organism:
Ursus maritimus
NCBI taxonomy Id: 29073
Other names: Thalarctos maritimus, U. maritimus, polar bear, white bear
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.