STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GPN2GPN-loop GTPase 2; Small GTPase required for proper localization of RNA polymerase II and III (RNAPII and RNAPIII). May act at an RNAP assembly step prior to nuclear import; Belongs to the GPN-loop GTPase family. (317 aa)    
Predicted Functional Partners:
GPN1
GPN-loop GTPase; Small GTPase required for proper nuclear import of RNA polymerase II (RNAPII). May act at an RNAP assembly step prior to nuclear import.
    
 
0.940
RPAP1
RNA polymerase II-associated protein 1.
    
 
 0.883
POLR2J
DNA-directed RNA polymerase II subunit RPB11-a.
    
 
 0.834
ENSUMAP00000015697
annotation not available
    
 
 0.802
ITSN2
LOW QUALITY PROTEIN: intersectin-2.
    
 0.800
POLR2B
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.791
POLR2C
DNA-directed RNA polymerase II subunit RPB3.
   
 
 0.738
ITSN1
Intersectin-1 isoform X2.
    
 0.698
ENSUMAP00000027695
annotation not available
    
 0.698
RPAP2
Putative RNA polymerase II subunit B1 CTD phosphatase RPAP2.
   
  
 0.598
Your Current Organism:
Ursus maritimus
NCBI taxonomy Id: 29073
Other names: Thalarctos maritimus, U. maritimus, polar bear, white bear
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.