STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RAP2CRas-related protein Rap-2c isoform X2. (117 aa)    
Predicted Functional Partners:
RAPGEF2
Rap guanine nucleotide exchange factor 2 isoform X2.
   
 0.941
RHOA
Ras homolog family member A.
   
 0.922
ITSN2
LOW QUALITY PROTEIN: intersectin-2.
   
 0.802
ITSN1
Intersectin-1 isoform X2.
    
 0.698
ENSUMAP00000027695
annotation not available
    
 0.698
RAPGEF4
Rap guanine nucleotide exchange factor 4 isoform X1.
    
 0.648
MET
Hepatocyte growth factor receptor.
   
 0.593
MST1R
Macrophage-stimulating protein receptor.
   
 0.593
NF1
Neurofibromin.
   
 0.527
LOC103671133
SH3 and multiple ankyrin repeat domains protein 1-like.
   
 0.520
Your Current Organism:
Ursus maritimus
NCBI taxonomy Id: 29073
Other names: Thalarctos maritimus, U. maritimus, polar bear, white bear
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.