TIMM8A protein (Ursus maritimus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

TIMM8A

Mitochondrial import inner membrane translocase subunit Tim8 A; Belongs to the small Tim family. (104 aa)

Predicted Functional Partners:

TIMM10

0.986

TIMM9

0.739

CHCHD4

0.737

TIMM10B

0.724

PHB2

0.713

MICU1

0.705

LOC103667908

0.701

TIMM22

0.699

ENSUMAP00000009285

0.678

MICU2

0.668

Your Current Organism:

Ursus maritimus

NCBI taxonomy Id: 29073
Other names: Thalarctos maritimus, U. maritimus, polar bear, white bear

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CHCHD4	ENSUMAP00000009285	ENSUMAP00000021712	ENSUMAP00000009285	Mitochondrial intermembrane space import and assembly protein 40.	annotation not available	0.725
CHCHD4	MICU1	ENSUMAP00000021712	ENSUMAP00000011985	Mitochondrial intermembrane space import and assembly protein 40.	Calcium uptake protein 1, mitochondrial isoform X1.	0.477
CHCHD4	MICU2	ENSUMAP00000021712	ENSUMAP00000020616	Mitochondrial intermembrane space import and assembly protein 40.	LOW QUALITY PROTEIN: calcium uptake protein 2, mitochondrial.	0.478
CHCHD4	TIMM10	ENSUMAP00000021712	ENSUMAP00000025108	Mitochondrial intermembrane space import and assembly protein 40.	Mitochondrial import inner membrane translocase subunit Tim10.	0.835
CHCHD4	TIMM10B	ENSUMAP00000021712	ENSUMAP00000000734	Mitochondrial intermembrane space import and assembly protein 40.	Mitochondrial import inner membrane translocase subunit Tim10 B.	0.686
CHCHD4	TIMM22	ENSUMAP00000021712	ENSUMAP00000013665	Mitochondrial intermembrane space import and assembly protein 40.	Mitochondrial import inner membrane translocase subunit Tim22 isoform X1.	0.517
CHCHD4	TIMM8A	ENSUMAP00000021712	ENSUMAP00000016531	Mitochondrial intermembrane space import and assembly protein 40.	Mitochondrial import inner membrane translocase subunit Tim8 A; Belongs to the small Tim family.	0.737
CHCHD4	TIMM9	ENSUMAP00000021712	ENSUMAP00000023021	Mitochondrial intermembrane space import and assembly protein 40.	Mitochondrial import inner membrane translocase subunit Tim9.	0.725
ENSUMAP00000009285	CHCHD4	ENSUMAP00000009285	ENSUMAP00000021712	annotation not available	Mitochondrial intermembrane space import and assembly protein 40.	0.725
ENSUMAP00000009285	LOC103667908	ENSUMAP00000009285	ENSUMAP00000021861	annotation not available	Mitochondrial import inner membrane translocase subunit TIM23; Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.	0.756
ENSUMAP00000009285	TIMM10	ENSUMAP00000009285	ENSUMAP00000025108	annotation not available	Mitochondrial import inner membrane translocase subunit Tim10.	0.981
ENSUMAP00000009285	TIMM10B	ENSUMAP00000009285	ENSUMAP00000000734	annotation not available	Mitochondrial import inner membrane translocase subunit Tim10 B.	0.883
ENSUMAP00000009285	TIMM22	ENSUMAP00000009285	ENSUMAP00000013665	annotation not available	Mitochondrial import inner membrane translocase subunit Tim22 isoform X1.	0.935
ENSUMAP00000009285	TIMM8A	ENSUMAP00000009285	ENSUMAP00000016531	annotation not available	Mitochondrial import inner membrane translocase subunit Tim8 A; Belongs to the small Tim family.	0.678
LOC103667908	ENSUMAP00000009285	ENSUMAP00000021861	ENSUMAP00000009285	Mitochondrial import inner membrane translocase subunit TIM23; Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.	annotation not available	0.756
LOC103667908	MICU1	ENSUMAP00000021861	ENSUMAP00000011985	Mitochondrial import inner membrane translocase subunit TIM23; Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.	Calcium uptake protein 1, mitochondrial isoform X1.	0.442
LOC103667908	PHB2	ENSUMAP00000021861	ENSUMAP00000004023	Mitochondrial import inner membrane translocase subunit TIM23; Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.	Prohibitin.	0.510
LOC103667908	TIMM10	ENSUMAP00000021861	ENSUMAP00000025108	Mitochondrial import inner membrane translocase subunit TIM23; Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.	Mitochondrial import inner membrane translocase subunit Tim10.	0.815
LOC103667908	TIMM10B	ENSUMAP00000021861	ENSUMAP00000000734	Mitochondrial import inner membrane translocase subunit TIM23; Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.	Mitochondrial import inner membrane translocase subunit Tim10 B.	0.756
LOC103667908	TIMM22	ENSUMAP00000021861	ENSUMAP00000013665	Mitochondrial import inner membrane translocase subunit TIM23; Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.	Mitochondrial import inner membrane translocase subunit Tim22 isoform X1.	0.869