STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
WWTR1WW domain-containing transcription regulator protein 1. (397 aa)    
Predicted Functional Partners:
TJP2
Tight junction protein ZO-2; Belongs to the MAGUK family.
   
 0.948
TBX5
T-box transcription factor TBX5.
    
 0.947
DVL2
LOW QUALITY PROTEIN: segment polarity protein dishevelled homolog DVL-2.
    
 0.944
KAT2B
Histone acetyltransferase KAT2B.
    
 0.927
TJP1
LOW QUALITY PROTEIN: tight junction protein ZO-1; Belongs to the MAGUK family.
   
 0.920
STK3
Serine/threonine-protein kinase 3.
    
 0.878
LATS1
Serine/threonine-protein kinase LATS1 isoform X1.
    
 0.877
LATS2
Non-specific serine/threonine protein kinase.
    
 0.865
TEAD4
Transcriptional enhancer factor TEF-3; Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis.
   
 0.858
SMAD4
Mothers against decapentaplegic homolog.
    
 0.840
Your Current Organism:
Ursus maritimus
NCBI taxonomy Id: 29073
Other names: Thalarctos maritimus, U. maritimus, polar bear, white bear
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.