STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CHRM3Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. (552 aa)    
Predicted Functional Partners:
CHRM5
Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins.
  
  
 
0.980
GNAQ
Guanine nucleotide-binding protein G(Q) subunit alpha.
    
 0.943
GRM5
Glutamate metabotropic receptor 5.
   
 
 0.925
KNG1
Kininogen-1 isoform X1.
     
  0.920
CHRM1
Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins.
  
  
 
0.920
BDKRB2
B2 bradykinin receptor; Belongs to the G-protein coupled receptor 1 family.
     
  0.905
GNA14
Guanine nucleotide-binding protein subunit alpha-14.
    
 0.827
GNA15
Guanine nucleotide-binding protein subunit alpha-15.
    
 0.823
GNAL
Guanine nucleotide-binding protein G(Olf) subunit alpha.
     
 0.652
ENSUMAP00000020007
Guanine nucleotide-binding protein G(s) subunit alpha.
     
 0.652
Your Current Organism:
Ursus maritimus
NCBI taxonomy Id: 29073
Other names: Thalarctos maritimus, U. maritimus, polar bear, white bear
Server load: low (24%) [HD]