node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ASF1A | ASF1B | ENSUMAP00000003388 | ENSUMAP00000005595 | Anti-silencing function 1A histone chaperone. | Histone chaperone ASF1B. | 0.603 |
ASF1A | PCNA | ENSUMAP00000003388 | ENSUMAP00000005923 | Anti-silencing function 1A histone chaperone. | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. | 0.412 |
ASF1A | PIF1 | ENSUMAP00000003388 | ENSUMAP00000017173 | Anti-silencing function 1A histone chaperone. | ATP-dependent DNA helicase PIF1; DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability. Efficiently unwinds G-quadruplex (G4) DNA structures and forked RNA-DNA hybrids. Resolves G4 structures, preventing replication pausing and double-strand breaks (DSBs) at G4 motifs. Involved in the maintenance of telomeric DNA. Inhibits telomere elongation, de novo telomere formation and telomere addition to DSBs via catalytic inhibition of telomerase. Reduces the processivity of telomerase by displacing active telomerase from DNA [...] | 0.658 |
ASF1A | POLA2 | ENSUMAP00000003388 | ENSUMAP00000013074 | Anti-silencing function 1A histone chaperone. | DNA polymerase alpha subunit B; Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis. | 0.460 |
ASF1A | RAD52 | ENSUMAP00000003388 | ENSUMAP00000018064 | Anti-silencing function 1A histone chaperone. | DNA repair protein RAD52 homolog isoform X1. | 0.535 |
ASF1A | WRN | ENSUMAP00000003388 | ENSUMAP00000009503 | Anti-silencing function 1A histone chaperone. | LOW QUALITY PROTEIN: Werner syndrome ATP-dependent helicase. | 0.555 |
ASF1B | ASF1A | ENSUMAP00000005595 | ENSUMAP00000003388 | Histone chaperone ASF1B. | Anti-silencing function 1A histone chaperone. | 0.603 |
ASF1B | PCNA | ENSUMAP00000005595 | ENSUMAP00000005923 | Histone chaperone ASF1B. | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. | 0.412 |
ASF1B | PIF1 | ENSUMAP00000005595 | ENSUMAP00000017173 | Histone chaperone ASF1B. | ATP-dependent DNA helicase PIF1; DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability. Efficiently unwinds G-quadruplex (G4) DNA structures and forked RNA-DNA hybrids. Resolves G4 structures, preventing replication pausing and double-strand breaks (DSBs) at G4 motifs. Involved in the maintenance of telomeric DNA. Inhibits telomere elongation, de novo telomere formation and telomere addition to DSBs via catalytic inhibition of telomerase. Reduces the processivity of telomerase by displacing active telomerase from DNA [...] | 0.658 |
ASF1B | POLA2 | ENSUMAP00000005595 | ENSUMAP00000013074 | Histone chaperone ASF1B. | DNA polymerase alpha subunit B; Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis. | 0.460 |
ASF1B | RAD52 | ENSUMAP00000005595 | ENSUMAP00000018064 | Histone chaperone ASF1B. | DNA repair protein RAD52 homolog isoform X1. | 0.555 |
ASF1B | WRN | ENSUMAP00000005595 | ENSUMAP00000009503 | Histone chaperone ASF1B. | LOW QUALITY PROTEIN: Werner syndrome ATP-dependent helicase. | 0.555 |
DNA2 | PCNA | ENSUMAP00000009946 | ENSUMAP00000005923 | LOW QUALITY PROTEIN: DNA replication ATP-dependent helicase/nuclease DNA2. | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. | 0.694 |
DNA2 | PIF1 | ENSUMAP00000009946 | ENSUMAP00000017173 | LOW QUALITY PROTEIN: DNA replication ATP-dependent helicase/nuclease DNA2. | ATP-dependent DNA helicase PIF1; DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability. Efficiently unwinds G-quadruplex (G4) DNA structures and forked RNA-DNA hybrids. Resolves G4 structures, preventing replication pausing and double-strand breaks (DSBs) at G4 motifs. Involved in the maintenance of telomeric DNA. Inhibits telomere elongation, de novo telomere formation and telomere addition to DSBs via catalytic inhibition of telomerase. Reduces the processivity of telomerase by displacing active telomerase from DNA [...] | 0.788 |
DNA2 | POLA2 | ENSUMAP00000009946 | ENSUMAP00000013074 | LOW QUALITY PROTEIN: DNA replication ATP-dependent helicase/nuclease DNA2. | DNA polymerase alpha subunit B; Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis. | 0.801 |
DNA2 | RAD52 | ENSUMAP00000009946 | ENSUMAP00000018064 | LOW QUALITY PROTEIN: DNA replication ATP-dependent helicase/nuclease DNA2. | DNA repair protein RAD52 homolog isoform X1. | 0.844 |
DNA2 | WRN | ENSUMAP00000009946 | ENSUMAP00000009503 | LOW QUALITY PROTEIN: DNA replication ATP-dependent helicase/nuclease DNA2. | LOW QUALITY PROTEIN: Werner syndrome ATP-dependent helicase. | 0.989 |
KIF18B | PIF1 | ENSUMAP00000019629 | ENSUMAP00000017173 | Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. | ATP-dependent DNA helicase PIF1; DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability. Efficiently unwinds G-quadruplex (G4) DNA structures and forked RNA-DNA hybrids. Resolves G4 structures, preventing replication pausing and double-strand breaks (DSBs) at G4 motifs. Involved in the maintenance of telomeric DNA. Inhibits telomere elongation, de novo telomere formation and telomere addition to DSBs via catalytic inhibition of telomerase. Reduces the processivity of telomerase by displacing active telomerase from DNA [...] | 0.704 |
KIF18B | TROAP | ENSUMAP00000019629 | ENSUMAP00000008712 | Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. | Tastin. | 0.832 |
ORC5 | PCNA | ENSUMAP00000025588 | ENSUMAP00000005923 | Origin recognition complex subunit 5 isoform X1. | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. | 0.505 |